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Simulation of Biological Systems (E374013)
Katedra:ústav přístrojové a řídící techniky (12110)
Zkratka:Schválen:09.01.2012
Platí do: ??Rozsah:2+2
Semestr:*Kredity:5
Zakončení:Z,ZKJazyk výuky:EN
Anotace
Modelling of biological dynamic systems, from single unit to population. Biological and artificial neuron, catastrophe theory, compartment models. Basic numerical description of dynamic systems and its solution in Matlab.
Vyučující
Ing. Vladimír Hlaváč Ph.D.
Zimní 2017/2018
doc. Ing. Ivo Bukovský Ph.D.
Letní 2016/2017
doc. Ing. Ivo Bukovský Ph.D.
Zimní 2016/2017
doc. Ing. Ivo Bukovský Ph.D.
Letní 2015/2016
doc. Ing. Ivo Bukovský Ph.D.
Zimní 2015/2016
Osnova
1-2. Introduction. The difference between the concepts of modeling technical and biological systems. Historical background- theory of catastrophes; Zeemans catastrophic machine.
3-4. Properties of nonlinear models of dynamic systems; periodic, quaziperiodic, and chaotic behavior of systems; deterministic chaos. Synchronization phenomenon of coupled biological systems.
5-6. Design principles of basic models of biological systems and their properties: population models, models of simple chemical reactions, cell regulation models, epidemiological model.
7-8. Design of dynamical model from measured data recordings (state-space reconstruction). Optimization of parameters of deterministic models: mathematical analysis, adaptation, genetic algorithms,...
9-10. Conventional and nonconventional models of a biological neuron. Possible utilization of artificial neural networks for modeling; advantages and disadvantages.
11-12. Approaches to the design of biological models featuring uncertainty; uncertainty in biological systems. Fuzzy model of the effect of combination of anesthetics with uncertainty in measured data.
13-14. Swarm intelligence, artificial ants (vant-s), population simulation.
Osnova cvičení
1-2 Useful programming techniques, worksheet calculators, introduction to Matlab,Maple, Simulink, efficency of matrix and vector operations in Matlab.
3-4 Fundamentals on modelling dynamical systems, linear s
3-4 Simulation of simple catastrophic models. Simulation of bifurcations in models of beetle population. Simulation of continuous chaotic model (MS Excel, demonstration of program Maple).
5-6 Determining parameters for state space reconstruction (False Neighbors Method, Mutual Information). Automated design of an artificial neural network model predicting heart-beat rhythm; designing a model from measured data (R-R recordings) (MS Excel, Dataplore, Matlab/Simulink).
7-8 Simulation of monitoring the actual changes in the dynamics of cardiovascular system with higher-order nonlinear neural units (HONNU) (Matlab/Simulink)
9-10 Automated design of adaptive neuro-fuzzy model of combined anesthetics effects with uncertainty in measured data (MS Excel, Matlab/Simulink ANFIS).
11-12 The model of the fast control influences of autonomous neural system affecting the heart-rate variability (Matlab/Simulink).
13-14 Accomplishing projects, consulting, credits
Literatura
Subject web page: http://iat.fs.cvut.cz/sbs/
Požadavky
Attending students should have accomplished basic course of mathematics on differential equations.
Klíčová slova
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